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  • Eye Health & Wellness

Eye Health and Dementia: Study finds Connection

  • Last updated November 3, 2022

6 min read

Heather Cottrell
Written byHeather Cottrell
Jovi Boparai, MD
Reviewed by Jovi Boparai, MD
Heather Cottrell
Heather Cottrell

Bio

Since becoming a Certified Health Coach in 2005, researching and creating content to help people live longer, healthier lives is my passion. As a content creator and online marketing coach for health coaches, I spend most of my time working on screens. Keeping my eyes healthy is important not just to my work, but to my life!

Get to know me a little better!

Hobby: creating content
Food: is coffee a food? ;)
Superhero: Wonder Woman
Guilty pleasure: bingewatching my favorite shows
Secret power: learning online tech quickly

Training:

Undergraduate: Fordham University
Health and wellness training: Institute for Integrative Nutrition

Jovi Boparai, MD
Jovi Boparai, MDCo-founder & CEO of CorneaCarePhiladelphia, PA

Bio

Dry eye disease is tough! I get it. I have struggled with dry eyes for several years from contact lens use, and from spending countless hours looking at computer screens. In college, my dry eyes got so bad that I couldn’t wear contact lenses, because of a constant “foreign body sensation” when I had them in. I had to stop reading every 30 minutes because my eyes would start to burn and my vision would get blurry. I tried a plethora of treatments and nothing seemed to work. Dry eye disease was not only impacting my eyes, but also my emotional wellbeing. It was preventing me from enjoying life, and getting in the way of my professional training. I felt overwhelmed, frustrated and hopeless.

It was only when I realized that my dry eyes were linked to my lifestyle, environment and overall health did things start to make sense. I noticed that on days when I spent less time on the computer, my eyes felt better. My symptoms would flare when it was windy, or when there was low humidity. I knew that if I wanted to get ahead of my dry eyes, I needed to not only treat my eyes, but to also address my lifestyle. I started a consistent regimen of artificial tears and eyelid hygiene. I switched from monthly contact lenses to daily contact lenses. I started taking scheduled breaks from looking at a computer. I ate a healthier diet focused on anti-inflammatory/antioxidants foods, and I bought a humidifier for my room. In the beginning doing all this seemed impossible, but over time it became part of my usual routine. Not only did my eyes feel better, but I was overall healthier and happier! Turns out what is good for my eyes, was also good for my mind and body. I carried this lesson with me as I started my career to become an ophthalmologist and ophthalmic surgeon.

Because of my personal journey and professional training, I believe dry eye treatment starts by listening to and empowering the patient. I listen for the struggles and cue in on their strengths, while picking up on their lifestyle. Only then do we together start building a treatment plan that incorporates good eye hygiene with small, but impactful lifestyle changes. Our sight is our most important sense, and it is intimately linked to our very being. I want dry eye patients to not only get their dry eyes under control, but to also enjoy good mental and physical health, and live a fulfilling life. What is good for the eyes should also strengthen the mind and fortify the body!

Get to know me a little better!

Hobby: vintage watches
Food: peanut butter
Superhero: Superman
Guilty pleasure: desserts
Secret power: has never had a headache

Training:

Undergraduate: University of Pittsburgh Honors College
Medical school: Weill Cornell Medicine
Ophthalmology residency: Wills Eye Hospital.

Eye Health and Dementia

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Table of Contents

Researchers have looked for a possible correlation between eye health and dementia. A new study found that eye diseases most common in older adults may be linked to an increased risk for dementia.

The UK Biobank study, published in the British Journal of Ophthalmology, studied more than 12,300 British adults, aged between 55 and 73, from 2006 to 2010, with a follow-up in early 2021.1

The study researched the links between systemic health conditions, vision impairments, and dementia. Systemic health conditions are those that affect the entire body, such as high blood pressure, diabetes, obesity, depression, and heart disease.

The study determined that the presence of these conditions along with certain eye diseases indicated a higher risk of dementia.

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Key Points

  • New study finds a connection between eye health and dementia.
  • Visual perception problems can be an early sign of dementia.
  • Understanding visual perception problems can help caregivers support a loved one with dementia.

What is Dementia?

Dementia describes a severe loss of memory, language, problem-solving, and other thinking skills that interfere with daily life. The primary cause of dementia is Alzheimer’s disease.2

Understanding the Different Types of Dementia

Dementia is not a single disease, but a general term that describes a range of different medical conditions caused by brain cell damage in certain areas of the brain. The outward symptoms in a person with dementia are serious memory loss and a decline in cognitive skills. The most common form of dementia is related to Alzheimer’s disease.3 

In Alzheimer’s disease elevated protein levels cause communication problems between brain cells in the hippocampus, the area of the brain responsible for learning and memory.3

Vascular dementia is the second most common cause of dementia. This type of dementia is caused by small bleeds and blocks in blood vessels in the brain. In the case of an adult with mixed dementia, more than one type of dementia is present.2

Additionally, there are reversible conditions such as thyroid problems and vitamin deficiencies that may cause symptoms of dementia.

Nutritional health and dry eye disease

The Link between Eye Health and Dementia

The UK Biobank study determined that the following conditions were related to a higher risk of dementia, even when occurring alone:

  • heart disease
  • stroke
  • diabetes
  • hypertension (high blood pressure)
  • depression

When age-related macular degeneration was diagnosed in patients with any of these conditions, an increased risk of dementia was also found. Further, the risk of dementia was greater than in people with only macular degeneration or a systemic condition.

The study also found that the risk of dementia was increased, though not as dramatically, in participants with cataracts and those with diabetic eye disease, compared with those without an ophthalmic condition.

It was also found that although glaucoma was not associated with a higher risk of Alzheimer’s disease or all-cause dementia, the study authors determined that the condition pointed to an increased risk of vascular dementia.

In cases where glaucoma was diagnosed in patients also diagnosed with heart disease, stroke, diabetes, depression, or high blood pressure, the risk for all-cause dementia was significantly higher.

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Risk Factors Similar for Dementia and Age-Related Eye Disease

The published study was unable to conclude a specific reason for the connection between eye health and dementia.

Vision problems are not uncommon in adults with known risk factors for dementia. Such risk factors include systemic health conditions such as heart disease, stroke, obesity, hypertension, diabetes, and depression.

In many cases of adults with dementia or Alzheimer’s disease, problems with visual perception manifest as an early symptom.4

The close relationship between the brain, the eyes, and visual perception, has scientists studying the possible connections between neurological conditions and eye health.4 Research shows that conditions related to brain cell damage, which includes both dementia and Alzheimer’s disease, also affect the retina.5

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These results make it imperative that healthcare providers understand the relationship between eye health and signs of dementia, and look for the risk factors, especially in older adults.

Further research could shed more light on the correlation between eye conditions and dementia risk. More research may determine if cognitive decline can be reduced by reversing vision loss.

Ways that Vision Changes with Age

In older adults, there is often a diminished ability to process visual stimulation. Medical conditions affecting vision, including cataracts, glaucoma, macular degeneration, and diabetes, are also associated with challenges around visual perception.

Age-related vision changes may include: 

  • Blurred vision
  • Difficulty reading and performing near-distance tasks
  • Trouble adjusting to bright lights 
  • Reduced peripheral vision 
  • Reduced ability to process depth perception
Key symptoms of dry eye disease

Visual Perception Changes in Adults with Alzheimer’s disease and Dementia

Visual perception is how the brain interprets what the eye sees. As people age, changes happen in the brain and in the eyes. Age-related eye diseases, including cataracts, glaucoma, or macular degeneration, can impair the visual data our eyes see and send to the brain.

These miscommunications between the eyes and the brain contribute to diminished cognitive thinking, memory problems, or even dementia. Hence, the study found a connection between eye health and dementia.

Taken from the other side, when the brain undergoes changes due to dementia or Alzheimer’s disease, the brain is no longer processing visual information the way it once did, creating confusion and disorientation.

How Vision Perception Problems Affect Adults with Dementia

The varied types of dementia deteriorate the visual-perceptual system in different ways. The visual perception issues most commonly found in adults with dementia are:

  • Diminished sensitivity to the contrast between objects and colors in the background
  • Trouble detecting movement of objects
  • Problems with depth perception 
  • Tendency to stare as shifting gaze becomes difficult
  • Difficulty recognizing faces
  • Reduced visual color palette
  • Visual hallucinations
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The vision problems that occur with dementia can affect your loved one’s daily life. These changes can cause frustration for them, and for their caregiver. It helps to understand what’s behind some of the unusual behaviors an adult with dementia may exhibit.

Lack of depth perception can cause adults with dementia to reach for objects that are actually on the ceiling, in a picture on the wall, or part of a television program, which can cause feelings of fear or frustration.

Patterned or uneven floors may create confusion as your loved one’s visual perception problems cause the floor to appear to have a step or other obstacle, causing apprehension.

The dementia patient may not recognize the food on their plate and struggle to eat meals or drink beverages, which can lead to weight loss, dehydration, vitamin deficiency, and other health conditions.

Eye Health and Dementia: How Caregivers Can Help

When your loved one is living with vision problems and Alzheimer’s disease or dementia, there are changes you can implement to help support your loved one’s autonomy in the home.

  • Turn lights up slowly, as the pupils in adults with Alzheimer’s disease adjust more gradually to light
  • Bright contrasting colors can help draw attention to important objects they need
  • Sit or stand directly in front of your loved one to speak with them, to compensate for diminished peripheral vision

These changes can help reduce agitation, confusion and nervousness for adults with dementia or Alzheimer’s disease.

For older adults, it’s important to have regular eye exams and practice good routine eye care. Be sure your loved one sees their eye doctor (optometrist or ophthalmologist) for a comprehensive eye exam which may help diagnose vision problems in their early stages.

Lifestyle Changes: balanced diet, working with the weather, taking regular breaks

Poor appetite and difficulty feeding themselves can lead to health problems. CorneaCare eye vitamins are specially formulated multivitamins that can supplement your loved one’s diet while supporting good eye health.

Aging adults are at increased risk for eye diseases including cataracts, glaucoma, and age-related macular degeneration6, all of which can further reduce the quality of life in people with dementia.

Putting it All Together

A recent study found a significant connection between systemic health conditions, eye disease, and dementia. This relationship suggests that managing these conditions with the help of your doctor and lifestyle changes, such as a healthy diet, having regular eye exams, and practicing good eye care, may reduce your risk factors for dementia.

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What’s Next

Learn to love your eyes! Read more eye health and wellness tips on our blog.

Bibliography

  1. Shang X, Zhu Z, Huang Y, et al. “Associations of ophthalmic and systemic conditions with incident dementia in the UK Biobank”, British Journal of Ophthalmology. Published Online First: 13 September 2021. doi: 10.1136/bjophthalmol-2021-319508, https://bjo.bmj.com/content/early/2022/07/07/bjophthalmol-2021-319508. Accessed 10 September 2022.
  2. “What is Dementia?” Alzheimer’s Association, https://www.alz.org/alzheimers-dementia/what-is-dementia. Accessed 10 September 2022.
  3. “What is Alzheimer’s Disease?” Alzheimer’s Association, https://www.alz.org/alzheimers-dementia/what-is-alzheimers. Accessed 10 September 2022.
  4. “Visual and Ocular Manifestations of Alzheimer’s Disease and Their Use as Biomarkers for Diagnosis and Progression”. NIH National Library of Medicine, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836138/. Accessed 11 September 2022.
  5. “Alzheimer’s Disease, Dementia and the Eye”. American Academy of Ophthalmology, https://www.aao.org/eye-health/diseases/alzheimers-disease-dementia-eye. Accessed 11 September 2022.
  6. “Common Age-Related Eye Problems”. Cleveland Clinic, https://my.clevelandclinic.org/health/articles/8567-common-age-related-eye-problems. Accessed 11 September 2022.

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